Eleusian acquisition & three provisional patents propel GreenStar Biosciences into the exciting world of Transformational Medicine - (CSE:GSTR | OTC:GTSIF)

By James Moore

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Mild traumatic brain injury (MTBI) – better known as concussion – is notoriously difficult to treat.

It affects as many as 2 million Americans each year.

While many patients tend to recover, subsequent mental health problems can have profound consequences on the rest of their lives.

For sufferers of post-traumatic stress disorder (“PTSD”) this is particularly acute.

The link between PTSD and concussion isn’t widely recognized.

Until relatively recently, the medical mainstream regularly misdiagnosed PTSD in those who had experienced concussion. Doctors would often incorrectly attribute a PTSD sufferer’s symptoms to post-concussion syndrome (PCS).

This misdiagnosis resulted in the administration of inappropriate and ineffective treatments, worsening the symptoms of what was actually PTSD to cause patients further distress and pain.

An unacceptably large number of former servicemen and women bore the brunt of this lack of understanding.

As many as 30% of combat veterans have reported suffering from PTSD.

Dealing with the mental health conditions of former service personnel is such a challenge that the U.S. Department of Veterans Affairs has allocated $10.2 billion in its 2021 budget to confront this crisis.

Concussion-inflicted PTSD is one of the main foes.

The trouble is that traditional therapies do not work nearly well enough.

Most people who receive a concussion – service personnel included – are simply advised to “wait it out”.

While this might succeed in alleviating the physical effects of the concussion (though even then that is a hit and miss gamble), it fails to address the traumatic experience that usually led to the concussion in the first place.

Questions have been asked about how best to resolve this issue in medical circles for a long time, but only very recent research has begun to provide some answers.

The key could lie in transformational medicines.

Transformational medicines represent a new branch of medical research, investigating the highly positive role psychedelic compounds could play in revolutionary new drugs to treat a broad range of mental health conditions.

Psychoactive substances, like MDMA, ketamine, and psilocybin are now being tested for their restorative powers.

The science has become so promising that regulatory authorities are quickly relaxing their stance towards these drugs and are even encouraging extensive research programs into their use.

Hundreds of millions of dollars have started to flow into the sector, in anticipation of creating a new frontier in drug discovery.

To emphasize how seriously U.S. authorities are taking the potential for transformational medicines consider that, in June, the U.S. Defense Advanced Research Projects Agency (DARPA) announced a $27 million research project into them to “create better psychiatric medicines.”

A number of companies have come to market over the last few months, hoping to capitalize on this immense opportunity.

However, one of the most recent entrants has an exceptionally compelling business case: GreenStar Biosciences (CSE:GSTR | OTC:GTSIF).

The phenomenal Eleusian Biosciences acquisition – a ready-made I.P. portfolio of transformational medicine projects

On 21 JulyGreenStar (CSE:GSTR | OTC:GTSIF) signed a definitive agreement to buy Eleusian Biosciences Corp., a privately-owned drug research and development company with immense potential in the transformational medicine space.

This deal was an amazing coup for GreenStar (CSE:GSTR | OTC:GTSIF) and its shareholders. It brought into the firm an almost unparalleled research capability and a pipeline of projects with blockbuster appeal.

Eleusian’s edge came a few years ago, when the firm’s founders learned about a remarkable new development at the University of Miami’s School of Medicine.

Here, researchers had revealed that an over-the-counter drug, n-acetylcysteine (“NAC”), could be a highly effective treatment for mTBI.

The team behind Eleusian immediately saw the great opportunity.

Driven by the belief that the mentally restorative properties of NAC could be combined with psychedelic compounds to make much more effective treatments, Eleusian forged a partnership with the University.

Together, they started to research and develop treatments for PTSD, pioneering this radically new approach.

This working relationship had already yielded two provisional patents.

Then, no sooner had the ink dried on the deal with GreenStar (CSE:GSTR | OTC:GTSIF), Eleusian announced it had filed its THIRD provisional patent.

This is the best possible news for GreenStar (CSE:GSTR | OTC:GTSIF), highlighting its immense speculative appeal moving forward.

Thanks to the Eleusian deal, GreenStar (CSE:GSTR | OTC:GTSIF) now has on its books these three extremely promising provisional patents:

The provisional patent for a combination therapy, using psilocybin and NAC for the treatment of mTBI with PTSD and PTSD alone

Another provisional patent for a combination therapy, using MDMA and NAC for the treatment of mTBI with PTSD and PTSD alone

A final provisional patent for a “nasal mist transducer” – a device that allows specific doses of different medicines to be sprayed into the nasal cavity and rapidly enter the bloodstream. GreenStar (CSE:GSTR | OTC:GTSIF) and Eleusian are now seeking strategic partners to build a prototype.

With such a comprehensive I.P. portfolio already in place following the Eleusian acquisition, GreenStar (CSE:GSTR | OTC:GTSIF) can now also pursue research into different applications of the NAC compound with other psychedelics.

The potential for pioneering drug discovery to treat a wide range of mental health conditions is immense:

From a standing start, GreenStar (CSE:GSTR | OTC:GTSIF) has broken into a sprint in the race to discover the first blockbuster transformational medicines.

Transformational medicines – a new dawn in drug discovery for GreenStar Biosciences (CSE:GSTR | OTC:GTSIF)

So, what is it that is causing so much interest in transformational medicines?

The simple answer is the science is so convincing.

Despite decades of political opposition to the use of psychedelic compounds in medicinal treatments, research carried on.

The incredible results, indicating the potential for long-term cures, could not be ignored.

Take psilocybin as an example.

One study by Johns Hopkins revealed a long-term success rate of 80% in a trial using repeated, small doses of psilocybin to treat anxiety in cancer patients.

In another study (results shown below), psilocybin was shown to be significantly more effective than any other treatment for depression over a sustained period of time.

Results from other research have been so impressive that the U.S. Food and Drug Administration (FDA) granted breakthrough therapy status for an MDMA-assisted psychotherapy for the treatment of PTSD in 2017. That is now underdoing Phase 3 clinical trials.

In 2018, the FDA awarded the same designation to the first psilocybin therapy aimed at healing treatment-resistant depression.

The FDA only awards this status to drug development programs that can demonstrate clear, preliminary clinical evidence that the new treatment can deliver a “substantial improvement” on at least one existing therapy.

More awards have since been granted, heralding a new dawn in drug discovery to cure mental health conditions.

With the research pedigree of Eleusian underpinning its new business model, GreenStar (CSE:GSTR | OTC:GTSIF) is now at the forefront of this exciting new field in blockbuster drug discovery.

This company’s focus on developing treatments for PTSD gives it a clear, competitive edge. Having already secured three provisional patents, GreenStar (CSE:GSTR | OTC:GTSIF) has a rich product pipeline and the opportunity to add to this through more research.

The second half of 2020 promises to be a thrilling ride for the company’s shareholders.


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Author: James Moore

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