How the ISM Manufacturing Index Influences Bitcoin and Ethereum Growth

By Patricia Miller

Dec 11, 2025

2 min read

Tom Lee connects the ISM manufacturing index rise to a potential crypto supercycle for Bitcoin and Ethereum.

What does the ISM manufacturing index mean for Bitcoin and Ethereum? Tom Lee, a leading voice from Fundstrat, connects the movement of the ISM manufacturing index above the pivotal 50 mark to a potential new bullish phase for Bitcoin and Ethereum. Historically, when the ISM index rises over this threshold, it often signals strong growth periods for these cryptocurrencies. This relationship suggests that investor sentiment may shift favorably toward digital assets when the economy hints at expansion.

The ISM manufacturing index serves as a significant indicator of economic health in the U.S. It aggregates data from purchasing managers on new orders, production levels, employment, and supplier deliveries into a diffusion index. A reading above 50 indicates that economic activity is on the rise, while a reading below 50 suggests a slowdown. Currently, the latest index reading is 48.2, suggesting a modest contraction.

What is the correlation between the ISM index and Bitcoin? Lee points out a strong correlation, especially when you consider Bitcoin's long-term trend. When you adjust Bitcoin's performance to eliminate long-term trends, its movement closely mirrors shifts in the ISM index. This suggests that changes in economic conditions could have a direct impact on Bitcoin's valuation.

Could Bitcoin's traditional cycle pattern be on the verge of disruption? Some experts, including Cathie Wood from ARK Invest, argue that the standard four-year cycle seen in Bitcoin's price patterns may not hold true this time around. Lee shares this perspective, indicating that new record highs for cryptocurrencies could emerge as soon as January.

He emphasizes the adaptability of Bitcoin to various market influences, noting its current responsiveness to monetary policy and the business cycle. As these factors begin to improve, it may lead to a reevaluation of expectations around Bitcoin's price in relation to its historical cycles. Investors who rely solely on past patterns may need to reconsider, as the landscape appears poised for significant changes soon.

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Important Notice And Disclaimer

This article does not provide any financial advice and is not a recommendation to deal in any securities or product. Investments may fall in value and an investor may lose some or all of their investment. Past performance is not an indicator of future performance.