Understanding Ethereum's Dominance in Onchain Finance

By Patricia Miller

May 22, 2026

2 min read

Ethereum is the backbone of onchain finance, dominating stablecoins and DeFi while attracting institutional interest and investments.

#How Significant is Ethereum in Onchain Finance?

Ethereum stands out as more than just a leading smart contract platform. It serves as a crucial foundation for many essential components in onchain finance, and the findings from Grayscale Research back this assertion with compelling data.

The research team, under the guidance of Zach Pandl, has calculated Ethereum's dominance in three main areas of onchain finance: stablecoins, decentralized finance, and tokenized real-world assets.

#What Do the Numbers Tell Us About Ethereum’s Leadership?

As of mid-2025, the Ethereum ecosystem, including its expanding Layer 2 networks, represents over 50% of all stablecoin balances. It also oversees around 45% of stablecoin transactions measured by dollar volume.

In decentralized finance (DeFi), Ethereum holds approximately 65% of the total value locked in various protocols. This statistic indicates that roughly two out of every three dollars utilized for lending, borrowing, and trading within DeFi reside on Ethereum.

When it comes to tokenizing US Treasury products, the situation is even more favorable for Ethereum. Nearly 80% of these tokenized government debt products are operating on its network, a clear indicator of institutional interest in the cryptocurrency sphere.

#Why Do Institutions Prefer Ethereum?

Prominent companies such as Coinbase, Kraken, and Sony have chosen to build their decentralized applications on Ethereum’s infrastructure. In July 2025, the price of ETH saw a significant boost of nearly 50%, coinciding with $5.4 billion in net inflows into exchange-traded products tied to ETH.

However, it is vital to note that strong onchain metrics do not always correlate directly to ETH's price performance. Historically, there has been an inconsistency between the network's usage statistics and the market price of ETH, which warrants caution.

#What Are the Competitive Challenges for Ethereum?

Despite Ethereum's impressive metrics, competitors like Solana and the BNB Chain continue to make strides in transaction speed and cost efficiency. If Ethereum is processing 45% of stablecoin transactions by dollar value, that leaves 55% of such activity taking place on alternative platforms.

While Ethereum's Layer 2 solutions aim to fill this gap, they also add complexity for users. Those navigating the various layers, such as Arbitrum, Optimism, and Base, often encounter challenges like bridging issues, liquidity fragmentation, and difficulty in tracking their assets across these different chains. The 50% stablecoin balance figure considers the total across this broader landscape.

#What Does This Mean for Investors?

The $5.4 billion in July's exchange-traded product inflows suggests that institutional investors view Ethereum as a reliable settlement layer for onchain finance. Institutional investment often has more stability than retail investments, potentially establishing a more consistent demand for ETH compared to previous market cycles.

Should Ethereum's Layer 2 networks capture the lion's share of future growth while transaction fees on the mainnet remain low, the value accumulation for ETH could present more complex considerations. Validators may experience reduced earnings as more activities transition to the rollups, even if the overall ecosystem flourishes.

Important Notice And Disclaimer

This article does not provide any financial advice and is not a recommendation to deal in any securities or product. Investments may fall in value and an investor may lose some or all of their investment. Past performance is not an indicator of future performance.